A New Quassinoid from Crude Quassin-extract of Quassia amara Article. Quassinoids from Picrasma Crenata Journal of Asian Natural Products Research. A new quassinoid, 2-dihydroailanthone, has been isolated from the bark of Ailanthus glandulosa. Its structure was established on the basis of spectroscopic data. ISSN: Online Available at International Journal of Herbal Medicine. Quassinoids and Their Chemotaxonomic Significance.

Author: Zoloktilar Arashilkree
Country: Cuba
Language: English (Spanish)
Genre: Life
Published (Last): 1 December 2016
Pages: 354
PDF File Size: 9.81 Mb
ePub File Size: 13.2 Mb
ISBN: 849-3-84552-552-3
Downloads: 52158
Price: Free* [*Free Regsitration Required]
Uploader: Samumi

Open J Synth Theory Appl ;2: Sitemap What’s New Feedback Disclaimer.

Antifeedant activity of quassinoids. For reproduction of material from PPS: Structural requirements of quassinoids for the inhibition of cell transformation. Information about reproducing material from RSC articles with jounral licences is available on our Permission Requests page.

Ancient Sci Life ; Ligand map interaction Click here to view. Active site identification with pocket information Click here to view.

J Nat Prod ;27; In vitro antimalarial activity of quassinoids from Eurycoma longifolia against Malaysian chloroquine-resistant Plasmodium falciparum isolates. An in silico approach. For reproduction of material from NJC: J Recept Signal Transduct Jpurnal ; If you are the author of this article you still need to obtain permission to reproduce the whole article in a third party publication with the exception of reproduction of the whole article in a thesis or dissertation.


Quassinoids are used in the present study to act against malarial dihydrofolate reductase Pf-DHFRa potential antimalarial target.

A new antimalarial quassinoid from Simaba orinocensis.

A well known plant product, quassinoids are known to have antimalarial activity. Biochem Biophys Res Commun ; Muhammad I, Samoylenko V. The ligands used for the study are the quassinoids. Transtational Medicinal Plants and Malaria. The present study proves the promising potential of quassinoids as novel drugs against malaria.

Go to our Instructions for using Copyright Clearance Center page for details. Back to tab navigation Download options Please wait Plant products as antimicrobial agents. The protein for the present study was imported from protein data bank with the PDB Id, 4dpd and was prepared for docking.

A new antimalarial quassinoid from Simaba orinocensis.

Past, present and future. Antimalarial activity of simalikalactone E, a new quassinoid from Quassia amara L. Kinetic properties of dihydrofolate reductase from wild-type and mutant Plasmodium vivax expressed in Escherichia coli.


Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Front Med Chem ;4: Expert Opin Drug Discov ;2: Clin Microbiol Rev ; Computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues.

Quassinoids with dock scores Click here to view. Biologically active quassinoids and their chemistry: Synthesis of optically active tetracyclic quassinoid skeleton T.

Author: admin